Fallout 76: How to Farm Mutations

In Fallout 76, a Mutation is a unique effect caused by radioactive exposure. When a player is contaminated by Rads, they may gain supernatural abilities such as super jumps, which are referred to as Mutations.

In total, there are 20 Mutations in Fallout 76, and players can have 19 of them simultaneously. With this guide, Appalachia survivors learn how to farm mutations without Caps and discover which ones are worth the effort.

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The Best Way to Farm Mutations in Fallout 76

To farm Mutations, players will need to enter the radioactive pool at the basement of the Emmett Mountain Disposal Site. Each time they do so, their character earns a random Mutation, and they can repeat the process until a desired effect is farmed.


It’s important to note that there is a limit to gaining Mutations from Rads. Players can get only one effect per server, meaning they will need to server-hop to be able to farm them.

Here’s a step-by-step guide for farming Mutations:

  • Go to the Emmett Mountain Disposal Site
  • Enter the contaminated pool in the basement.
  • Rinse unwanted Mutations in the Contamination Shower and repeat the process.
  • Equip the Starched Genes Perk Card to secure the desirable Mutation.

A maxed-out Starched Genes perk prevents Contamination Showers and RadAway serums from washing the Mutations away. As a result, when players get a practical effect, they will need to have this card equipped to keep it on their characters.

The Best Perks for Farming Mutations in Fallout 76

Fallout 76 perk card packs pay to win

Ideally, players farming Mutations must have maxed-out Starched Genes, Class Freak, and Strange in Numbers Perk Cards. With the first card, Starched Genes, Mutations become permanent. The second card, Class Freak, reduces the negative effects of Mutations by up to 75%. The third card, Strange in Numbers, boosts Mutations’ effects in a team of mutants.

The Best Mutations to Farm in Fallout 76

Fallout 76 Run Away

Out of all 20 Mutations in Fallout 76, the best ones are Adrenal Reaction, Healing Factor, Speed Demon, and Marsupial. Adrenal Reaction increases weapon damage when HP is low, Healing Factor boosts HP regen by +300%, Speed Demon accelerates running and reloading by 20%, and Marsupial gives extra jump power and Carry Weight.

How to Get a Specific Mutation in Fallout 76

image showing modus, and ai companion, in fallout 76.

The only way to get a particular Mutation is by drinking its serum. Players can buy Mutation Serums from Vendors or get their recipes from the MODUS Science Terminals at the Whitespring Bunker.

Fallout 76 is available now for PC, PlayStation 4, and Xbox One.

MORE: How to Farm Lead in Fallout 76

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